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Infection of the stomach with H. pylori does not necessarily cause illness: over half of the global population is infected, but most individuals are asymptomatic. [7] [8] Persistent colonization with more virulent strains can induce a number of gastric and non-gastric disorders. [9]
Acid peptic diseases, such as peptic ulcers, Zollinger-Ellison syndrome, and gastroesophageal reflux disease, are caused by distinct but overlapping pathogenic mechanisms involving acid effects on mucosal defense. Acid reflux damages the esophageal mucosa and may also cause laryngeal tissue injury, leading to the development of pulmonary ...
Krienitz finds bacteria in the stomach of people with gastric cancer. [2] Turck feeds dogs Bacillus coli and produces ulcers. [7] 1907 Berkley Moynihan suggests that acid is a cause of ulcers. [1] 1910 Schwartz publishes the excess acid theory of the ulcer, coining the famous phrase "no acid, no ulcer." [2]
British: Gastro-oesophageal reflux disease (GORD); [1] gastric reflux disease, acid reflux disease, reflux, gastroesophageal reflux: X-ray showing radiocontrast from the stomach (white material below diaphragm) entering the esophagus (three vertical collections of white material in the mid-line of the chest) due to severe reflux: Pronunciation
In 1982, they performed the initial culture of H. pylori and developed their hypothesis on the bacterial cause of peptic ulcers and gastric cancer. [9] It has been claimed that the H. pylori theory was ridiculed by established scientists and doctors, who did not believe that any bacteria could live in the acidic environment of the stomach ...
Common causes include infection with Helicobacter pylori and non-steroidal anti-inflammatory drugs (NSAIDs). [1] Other, less common causes include tobacco smoking, stress as a result of other serious health conditions, Behçet's disease, Zollinger–Ellison syndrome, Crohn's disease, and liver cirrhosis.
There is erosive gastritis, for which the common causes are stress, alcohol, some drugs, such as aspirin and other nonsteroidal anti-inflammatory drugs , and Crohn's disease. And, there is non-erosive gastritis, for which the most common cause is a Helicobacter pylori infection. [15] [1]
[17] [4] Non-infectious causes are seen on occasion, but they are less likely than a viral or bacterial cause. [1] Risk of infection is higher in children due to their lack of immunity. [1] Children are also at higher risk because they are less likely to practice good hygiene habits. [1] Children living in areas without easy access to water and ...
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