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Biobanks can give researchers access to data representing a large number of people. Samples in biobanks and the data derived from those samples can often be used by multiple researchers for cross purpose research studies. For example, many diseases are associated with single-nucleotide polymorphisms.
DDBJ (Japan), GenBank (USA) and European Nucleotide Archive (Europe) are repositories for nucleotide sequence data from all organisms. All three accept nucleotide sequence submissions, and then exchange new and updated data on a daily basis to achieve optimal synchronisation between them.
Biological data comes in many formats. These formats include text, sequence data, protein structure and links. Each of these can be found from certain sources, for example: [citation needed] Text formats are provided by PubMed and OMIM. Sequence data is provided by GenBank, in terms of DNA, and UniProt, in terms of protein.
Also biobanks, which do specimen storage, cannot take full responsibility for specimen integrity, because before they take custody of samples someone must collect and process them and effects such as RNA degradation are more likely to occur from delayed sample processing than inadequate storage.
The National Institute of Neurological Disorders and Stroke (NINDS) Human Cell and Data Repository maintains a collection of cell lines to advance the study of neurological disorders. [ 7 ] [ 8 ] The National Institute on Aging (NIA) Aging Cell Repository facilitates research into the mechanisms of aging by providing cell lines collected from ...
A biobank is a physical place which stores biological specimens.In some cases, participant data is also collected and stored. Access policies details may vary across biobanks but generally involve obtaining ethics approval from institutional review boards (IRB) and scientific review or peer review approval from the institutions under which the biobanks operate as well as Ethics approval from ...
Metadata adds one layer of abstraction to this definition– it is data about the structures that contain data. Metadata may describe the structure of any data, of any subject, stored in any format. A well-designed metadata repository typically contains data far beyond simple definitions of the various data structures. Typical repositories ...
Systems biology is the computational and mathematical analysis and modeling of complex biological systems.It is a biology-based interdisciplinary field of study that focuses on complex interactions within biological systems, using a holistic approach (holism instead of the more traditional reductionism) to biological research.