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Olanzapine, sold under the brand name Zyprexa among others, is an atypical antipsychotic primarily used to treat schizophrenia and bipolar disorder. [13] It is also sometimes used off-label for treatment of chemotherapy-induced nausea and vomiting [ 14 ] and as an appetite stimulant . [ 15 ]
A Cochrane review comparing quetiapine to other atypical antipsychotic agents tentatively concluded that it may be less efficacious than olanzapine and risperidone; produce fewer movement related side effects than paliperidone, aripiprazole, ziprasidone, risperidone and olanzapine; and produce weight gain similar to risperidone, clozapine and ...
whereas only quetiapine has demonstrated efficacy as a monotherapy in non-psychotic MDD. [40] Olanzapine/fluoxetine is an efficacious treatment in both psychotic and non-psychotic MDD. [41] [42] Aripiprazole, brexpiprazole, cariprazine, olanzapine, and quetiapine have been approved as adjunct treatment for MDD by the FDA in the United States.
Another review found a link between cannabis use and an increased risk of developing mania and experiencing ... (Zyprexa®) Cariprazine (Vraylar®) Lurasidone (Latuda®) Quetiapine ER (Seroquel XR®)
At least five atypical antipsychotics (lumateperone, [48] cariprazine, [49] lurasidone, [50] olanzapine, [51] and quetiapine [52]) have also been found to possess efficacy in the treatment of bipolar depression as a monotherapy, whereas only olanzapine [53] and quetiapine [54] [55] have been proven to be effective broad-spectrum (i.e., against ...
Olanzapine/fluoxetine could produce a severe allergic reaction and should not be used if the patient has previously experienced an allergic reaction to either fluoxetine or olanzapine. [9] Olanzapine is correlated with an increase in blood sugar. Patients with diabetes, or those at risk for developing it, require careful monitoring. [9]
Common adverse effects of olanzapine, occurring from 1–10%, include: Gynecomastia [8]; Extrapyramidal symptoms (EPS) (dose-dependent). Tends to produce less extrapyramidal side effects than typical antipsychotics but more extrapyramidal side effects than sertindole, clozapine and quetiapine.
The antipsychotic quetiapine is typically dosed two to three times daily for the management of schizophrenia. [3] A simpler regimen would be a once daily administered antipsychotic. [1] For example, risperidone can be administered once daily. [4] A lack of adherence can lead to poor health outcomes, as well as unnecessary financial burden. [5]
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"About 50% of US physicians advise patients consult GoodRx." - Fortune