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Sirtuin 1, also known as NAD-dependent deacetylase sirtuin-1, is a protein that in humans is encoded by the SIRT1 gene. [5] [6] [7]SIRT1 stands for sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae), referring to the fact that its sirtuin homolog (biological equivalent across species) in yeast (Saccharomyces cerevisiae) is Sir2.
4837 18113 Ensembl ENSG00000166741 ENSMUSG00000032271 UniProt P40261 O55239 RefSeq (mRNA) NM_006169 NM_001311062 NM_010924 RefSeq (protein) NP_006160 NP_001358974 NP_001358975 NP_001358976 NP_001297991 NP_035054 Location (UCSC) Chr 11: 114.26 – 114.31 Mb Chr 9: 48.5 – 48.52 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Nicotinamide N-methyltransferase (NNMT) is an enzyme that ...
[4] [5] [6] The name Sir2 comes from the yeast gene 'silent mating-type information regulation 2', [7] the gene responsible for cellular regulation in yeast. From in vitro studies, sirtuins were thought to be implicated in influencing cellular processes like aging , transcription , apoptosis , inflammation [ 8 ] and stress resistance, as well ...
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UniProt is a freely accessible database of protein sequence and functional information, many entries being derived from genome sequencing projects. It contains a large amount of information about the biological function of proteins derived from the research literature.
A pair of geta. Geta (pl. geta) [1] are traditional Japanese footwear resembling flip-flops.A kind of sandal, geta have a flat wooden base elevated with up to three (though commonly two) "teeth", held on the foot with a fabric thong, which keeps the foot raised above the ground.
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