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Hospital-acquired pneumonia (HAP) is the second most common nosocomial infection and accounts for approximately one-fourth of all infections in the intensive care unit (ICU). [48] HAP, or nosocomial pneumonia, is a lower respiratory infection that was not incubating at the time of hospital admission and that presents clinically two or more days ...
Bloodstream infections (BSIs) are infections of blood caused by blood-borne pathogens. [1] The detection of microbes in the blood (most commonly accomplished by blood cultures [2]) is always abnormal. A bloodstream infection is different from sepsis, which is characterized by severe inflammatory or immune responses of the host organism to ...
The following outline is provided as an overview of and topical guide to concepts related to infectious diseases in humans.. Infection – transmission, entry/invasion after evading/overcoming defense, establishment, and replication of disease-causing microscopic organisms (pathogens) inside a host organism, and the reaction of host tissues to them and to the toxins they produce.
Hospital acquired pneumonia is the second most common nosocomial infection (after urinary tract infections) and accounts for 15–20% of the total. [ 1 ] [ 2 ] [ 3 ] It is the most common cause of death among nosocomial infections and is the primary cause of death in intensive care units .
Severe sepsis causes poor organ function or blood flow. [9] The presence of low blood pressure, high blood lactate, or low urine output may suggest poor blood flow. [9] Septic shock is low blood pressure due to sepsis that does not improve after fluid replacement. [9] Sepsis is caused by many organisms including bacteria, viruses, and fungi. [10]
A blood-borne disease is a disease that can be spread through contamination by blood and other body fluids. Blood can contain pathogens of various types, chief among which are microorganisms , like bacteria and parasites , and non-living infectious agents such as viruses .
Staphylococcus aureus is a leading cause of bloodstream infections throughout much of the industrialized world. [44] Infection is generally associated with breaks in the skin or mucosal membranes due to surgery, injury, or use of intravascular devices such as cannulas, hemodialysis machines, or hypodermic needles.
Histoplasmosis can be diagnosed by samples containing the fungus taken from sputum (via bronchoalveolar lavage), blood, or infected organs. In the majority of immunocompetent individuals, histoplasmosis resolves without any treatment. Typical treatment of severe disease first involves treatment with amphotericin B, followed by oral itraconazole. No