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Prednisone is a synthetic glucocorticoid used for its anti-inflammatory and immunosuppressive properties. [36] [37] Prednisone is a prodrug; it is metabolised in the liver by 11-β-HSD to prednisolone, the active drug. Prednisone has no substantial biological effects until converted via hepatic metabolism to prednisolone. [38]
Deflazacort's potency is around 70–90% that of prednisone. [8] A 2017 review found its activity of 7.5 mg of deflazacort is approximately equivalent to 25 mg cortisone, 20 mg hydrocortisone, 5 mg of prednisolone or prednisone, 4 mg of methylprednisolone or triamcinolone, or 0.75 mg of betamethasone or dexamethasone.
The company was founded by pharmacist Murray Koffler in 1962; [2] the Koffler family still retains ownership of the Super-Pharm pharmacy, which has locations in Israel, Poland, and formerly in China (as Ensure from 2005 to 2011). [5] Super-Pharm's logo is similar to that of Shoppers Drug Mart, which was created by the artist Sylvain Liu.
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[5] [6] Its elimination half-life is shorter in children compared to adults. [5] In another study, the elimination half-life of hydroxyzine in elderly adults was 29.3 hours. [7] One study found that the elimination half-life of hydroxyzine in adults was as short as 3 hours, but this may have just been due to methodological limitations. [54]
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Walmart Canada is a Canadian retail corporation, discount retailer and the Canadian subsidiary of the U.S.-based multinational retail conglomerate Walmart.Headquartered in Mississauga, Ontario, it was founded on March 17, 1994, with the purchase of the Woolco Canada chain from the F. W. Woolworth Company.
Empire operates . Lawtons; Needs Convenience; Farm Boy; Foodland some CO-OP stores in Atlantic Canada; FreshCo; IGA / IGA Extra in Alberta, Manitoba, Quebec, some parts of Atlantic Canada formerly CO-OP Atlantic and Saskatchewan only