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2. Bottom-up proteomics - Wikipedia

   en.wikipedia.org/wiki/Bottom-up_proteomics

   Essentially, bottom-up proteomics is a relatively simple and reliable means of determining the protein make-up of a given sample of cells, tissues, etc. [5] In bottom-up proteomics, the crude protein extract is enzymatically digested, followed by one or more dimensions of separation of the peptides by liquid chromatography coupled to mass ...

3. List of mass spectrometry software - Wikipedia

   en.wikipedia.org/wiki/List_of_mass_spectrometry...

   MetaMorpheus is a proteomics search software developed at the University of Wisconsin-Madison with integrated calibration, post-translational modification discovery, bottom-up and top-down proteomics search, cross-linking mass spectrometry (XL-MS) search, proteogenomic search, and label-free quantification (LFQ) capabilities. [7] MSFragger Freeware

4. Shotgun proteomics - Wikipedia

   en.wikipedia.org/wiki/Shotgun_proteomics

   Targeted proteomics using SRM and data-independent acquisition methods are often considered alternatives to shotgun proteomics in the field of bottom-up proteomics. While shotgun proteomics uses data-dependent selection of precursor ions to generate fragment ion scans, the aforementioned methods use a deterministic method for acquisition of ...

5. Bruker (BRKR) Advances in Proteomics Workflow With New ... - AOL

   www.aol.com/news/bruker-brkr-advances-proteomics...

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6. List of protein structure prediction software - Wikipedia

   en.wikipedia.org/wiki/List_of_protein_structure...

   Constituent amino-acids can be analyzed to predict secondary, tertiary and quaternary protein structure. This list of protein structure prediction software summarizes notable used software tools in protein structure prediction, including homology modeling, protein threading, ab initio methods, secondary structure prediction, and transmembrane helix and signal peptide prediction.

7. List of open-source bioinformatics software - Wikipedia

   en.wikipedia.org/wiki/List_of_open-source...

   A workflow management system used for building and running scalable and reproducible bioinformatics pipelines, especially in cloud and high-performance computing environments. Linux, macOS, Windows: Apache License 2.0 Nextflow Team [6] PathVisio: Desktop software for drawing, analyzing, and visualizing biological pathways Linux, macOS, Windows ...

8. ProteoWizard - Wikipedia

   en.wikipedia.org/wiki/ProteoWizard

   ProteoWizard is a set of open-source, cross-platform tools and libraries for proteomics data analyses. [1] [2] It provides a framework for unified mass spectrometry data file access and performs standard chemistry and LCMS dataset computations. Specifically, it is able to read many of the vendor-specific, proprietary formats and converting the ...

9. Mascot (software) - Wikipedia

   en.wikipedia.org/wiki/Mascot_(software)

   Mascot identifies proteins by interpreting mass spectrometry data. The prevailing experimental method for protein identification is a bottom-up approach, where a protein sample is typically digested with trypsin to form smaller peptides. While most proteins are too large, peptides usually fall within the limited mass range that a typical mass ...