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There are several classes of drugs for acid-related disorders, such as dyspepsia, peptic ulcer disease (PUD), gastroesophageal reflux disease (GORD/GERD), or laryngopharyngeal reflux. The World Health Organization gives drugs in these classes the categorization code ATC code A02.
High dose or long-term use of PPIs carries an increased risk of bone fractures which was not found with short-term, low dose use; the FDA included a warning regarding this on PPI drug labels in 2010. [23] In infants, acid suppression therapy is frequently prescribed to treat symptomatic gastroesophageal reflux in otherwise healthy infants (that ...
Pantoprazole, sold under the brand name Protonix, among others, is a medication used for the treatment of stomach ulcers, short-term treatment of erosive esophagitis due to gastroesophageal reflux disease (GERD), maintenance of healing of erosive esophagitis, and pathological hypersecretory conditions including Zollinger–Ellison syndrome.
Omeprazole also inhibits both basal and stimulated acid secretion irrespective of the stimulus [52] as it blocks the last step in acid secretion. [52] The drug binds non-competitively so it has a dose-dependent effect. [53] The inhibitory effect of omeprazole occurs within 1 hour after oral administration. The maximum effect occurs within 2 hours.
Medications such as NSAIDs, certain blood pressure drugs, and anti-cholinergic medications, may weaken the lower esophageal sphincter. Treatments for acid reflux
Famotidine, sold under the brand name Pepcid among others, is a histamine H 2 receptor antagonist medication that decreases stomach acid production. [4] It is used to treat peptic ulcer disease, gastroesophageal reflux disease, and Zollinger–Ellison syndrome. [4] It is taken by mouth or by injection into a vein. [4] It begins working within ...
People with certain risk factors—including being over 50, male, white, a smoker, and having obesity or a history of acid reflux—could also make you eligible for esophageal cancer screening.
Rabeprazole, sold under the brand name Aciphex, among others, is a medication that decreases stomach acid. [6] It is used to treat peptic ulcer disease, gastroesophageal reflux disease, and excess stomach acid production such as in Zollinger–Ellison syndrome. [6]
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