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Rasburicase is approved for use by the U.S. Food and Drug Administration (and European counterparts) for the prevention and treatment of tumor lysis syndrome (TLS) [6] in people receiving chemotherapy for hematologic cancers such as leukemias and lymphomas. However, it is not clear if it results in important benefits such as decreased kidney ...
Luteolin-7-O-glucuronide is a chemical compound that is classified as a flavone. It is found in Acanthus hirsutus [1] and in rye (Secale cereale). [2] [3] Metabolism
The systematic name of this enzyme class is UDP-glucuronate:luteolin-7-O-beta-D-glucuronide 2''-O-glucuronosyltransferase. Other names in common use include uridine diphosphoglucuronate-luteolin 7-O-glucuronide , glucuronosyltransferase , LMT , and UDP-glucuronate:luteolin 7-O-glucuronide-glucuronosyltransferase .
If you have frequent gout flares, gout associated with tophi, or joint damage, your provider may prescribe medication to lower uric acid levels. These can help prevent gout flares and further ...
Luteolin is a flavone, a type of flavonoid, with a yellow crystalline appearance. [ 1 ] Luteolin is the main yellow dye from the Reseda luteola plant, used for dyeing since at least the first millennium B.C. Luteolin was first isolated in pure form, and named, in 1829 by the French chemist Michel Eugène Chevreul .
Gout (/ ɡ aʊ t / GOWT [7]) is a form of inflammatory arthritis characterized by recurrent attacks of pain in a red, tender, hot, and swollen joint, [2] [8] caused by the deposition of needle-like crystals of uric acid known as monosodium urate crystals. [9]
The NSAID diclofenac has an antiuricosuric action, which may be partly responsible for the extraordinary toxicity of this drug in vultures. [6] Pyrazinamide, a drug indicated only for treatment of tuberculosis, is a potent antiuricosuric [7] and, as a consequence, has an off-label use in the diagnosis of causes of abnormal uric acid clearance. [8]
The systematic name of this enzyme class is UDP-glucuronate:luteolin-7-O-beta-D-diglucuronide 4'-O-glucuronosyltransferase. Other names in common use include uridine diphosphoglucuronate-luteolin 7-O-diglucuronide , glucuronosyltransferase , UDP-glucuronate:luteolin 7-O-diglucuronide-glucuronosyltransferase , UDPglucuronate:luteolin , 7-O ...
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