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Interneurons (also called internuncial neurons, association neurons, connector neurons, or intermediate neurons) are neurons that are not specifically motor neurons or sensory neurons. Interneurons are the central nodes of neural circuits , enabling communication between sensory or motor neurons and the central nervous system (CNS). [ 2 ]
In neuroscience, Golgi cells are the most abundant inhibitory interneurons found within the granular layer of the cerebellum. [1] Golgi cells can be found in the granular layer at various layers. [2] The Golgi cell is essential for controlling the activity of the granular layer. [3] They were first identified as inhibitory in 1964. [4]
Basket cells are multipolar GABAergic interneurons that function to make inhibitory synapses and control the overall potentials of target cells. In general, dendrites of basket cells are free branching, contain smooth spines, and extend from 3 to 9 mm. Axons are highly branched, ranging in total from 20 to 50mm in total length.
It samples information from the Purkinje cell axon collaterals and forwards this information to the molecular and granular layers of the cerebellum. The axons of the Lugaro cells only contact inhibitory interneurons such as the basket, stellate and Golgi cells. The parallel axon targets stellate and basket cells and the transverse axon targets ...
The parallel fibers and ascending axon synapses from the same granule cell fire in synchrony which results in excitatory signals. In the cerebellar cortex there are a variety of inhibitory neurons (interneurons). The only excitatory neurons present in the cerebellar cortex are granule cells. [10]
They develop in the cerebellar primordium that covers the fourth ventricle and below a fissure-like region called the isthmus of the developing brain. Purkinje cells migrate toward the outer surface of the cerebellar cortex and form the Purkinje cell layer. Purkinje cells are born during the earliest stages of cerebellar neurogenesis.
The Federative International Committee on Anatomical Terminology (FICAT), which is a subcommittee of the International Federation of Associations of Anatomists (IFAA), officially recognized the “unipolar brush cell” as a new cell type of the cerebellar cortex in 2008. [5]
The human cerebellum is located at the base of the brain, with the large mass of the cerebrum above it, and the portion of the brainstem called the pons in front of it. It is separated from the overlying cerebrum by a layer of tough dura mater called the cerebellar tentorium; all of its connections with other parts of the brain travel through the pons.