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The role for these products is between just the use of simple analgesics (paracetamol or ibuprofen) and the triptan class of drugs; although the latter are not options during pregnancy. [7] In the elderly although triptans are generally avoided, so too are antiemetics such as metoclopramide due to higher risks of side effects.
Metoclopramide is a medication used to treat nausea, vomiting, gastroparesis, and gastroesophageal reflux disease. [5] It is also used to treat migraine headaches. [6]Common side effects include feeling tired, diarrhea, akathisia, and tardive dyskinesia.
Metopimazine is an approved prescription drug in France under the brand name Vogalene® [8] that has been used for the treatment of nausea and vomiting. [9] Vogalene® is available under different forms, including 15 mg capsules, 7.5 mg orally disintegrating tablets, 5 mg suppository, 0.1% oral liquid, and a 10 mg/mL intravenous (IV) solution approved for the prevention of chemotherapy-induced ...
An antiemetic is a drug that is effective against vomiting and nausea. Antiemetics are typically used to treat motion sickness and the side effects of opioid analgesics, general anaesthetics, and chemotherapy directed against cancer. They may be used for severe cases of gastroenteritis, especially if the patient is dehydrated. [1] [2]
Bulking agents like methylcellulose, guar gum or plant fibre (bran, sterculia, isabgol, etc.) are used for diarrhoea in functional bowel disease and to control ileostomy output. Absorbents absorb toxic substances that cause infective diarrhoea, methylcellulose is an absorbent.
In the 1970s, John Fozard found that metoclopramide and cocaine were weak antagonists at the 5-HT 3 (5-HT-M) receptor. Fozard and Maurice Gittos later synthesized MDL 72222, the first potent and truly selective 5-HT 3 receptor antagonist. [35] [36] The antiemetic effects of metoclopramide were found to be partially because of its serotonin ...
In children, the most accurate signs of moderate or severe dehydration are a prolonged capillary refill, poor skin turgor, and abnormal breathing. [23] [41] Other useful findings (when used in combination) include sunken eyes, decreased activity, a lack of tears, and a dry mouth. [1] A normal urinary output and oral fluid intake is reassuring. [23]
Cyclizine, sold under a number of brand names, is a medication used to treat and prevent nausea, vomiting and dizziness due to motion sickness or vertigo. [2] It may also be used for nausea after general anaesthesia or that which developed from opioid use. [2] [3] It is taken by mouth, in the rectum, or injected into a vein. [3] [4]
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