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Calcitriol is a hormone and the active form of vitamin D, normally made in the kidney. [8] [9] [10] It is also known as 1,25-dihydroxycholecalciferol.It binds to and activates the vitamin D receptor in the nucleus of the cell, which then increases the expression of many genes. [11]
One common active form is 1,25-dihydroxyvitamin D. [4] The term vitamin D in this article means cholecalciferol, ergocalciferol, 25-hydroxyvitamin D, and the active forms. The role of vitamin D is best characterized as enabling calcium absorption and regulating calcium homeostasis. Vitamin D also play a role in phosphate absorption. [5]
In 1969, a specific binding protein for vitamin D called the vitamin D receptor was identified. [221] Shortly thereafter, the conversion of vitamin D to calcifediol and then to calcitriol, the biologically active form, was confirmed. [222] The photosynthesis of vitamin D 3 in skin via previtamin D 3 and its subsequent metabolism was described ...
Vitamin D is essential for the bones and teeth, the immune system, brain health, and for regulating inflammation. The body produces vitamin D as a response to sun exposure. Certain foods and ...
The two most common forms are vitamin D2 and vitamin D3. Vitamin D is a fat-soluble vitamin which plays a major role in bone health, immunity, and nerve communication between the brain and muscle ...
Cholecalciferol is a form of vitamin D which is naturally synthesized in skin and functions as a pro-hormone, being converted to calcitriol. This is important for maintaining calcium levels and promoting bone health and development. [4] As a medication, cholecalciferol may be taken as a dietary supplement to prevent or to treat vitamin D ...
Vitamin C- Water-soluble vitamin that aids in keeping tissues healthy, wound healing, and infection prevention. [2] Vitamin D- Normally, the kidney changes vitamin D into its active form, vitamin D3, which helps with calcium absorption. Many dialysis patients have low intakes of calcium due to avoidance of foods containing phosphorus and potassium.
There's lots of confusion around the difference between vitamin D2 and vitamin D3, and which is best for whom. Doctors and experts explain.
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