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It contains lisinopril, an ACE inhibitor, and hydrochlorothiazide, a diuretic. [2] [3] Typically, it becomes an option once a person is doing well on the individual components. [4] It is taken by mouth. [3] Common side effects include dizziness, headache, cough, and feeling tired. [2] Severe side effects may include angioedema and low blood ...
Lisinopril is a medication belonging to the drug class of angiotensin-converting enzyme (ACE) inhibitors and is used to treat hypertension (high blood pressure), heart failure, and heart attacks. [7] For high blood pressure it is usually a first-line treatment. It is also used to prevent kidney problems in people with diabetes mellitus. [7]
A persistent dry cough is a relatively common adverse effect believed to be associated with the increases in bradykinin levels produced by ACE inhibitors, although the role of bradykinin in producing these symptoms has been disputed. [24] Many cases of cough in people on ACE inhibitors may not be from the medication itself, however. [25]
The most common symptom of eosinophilic bronchitis is a chronic dry cough lasting more than 6–8 weeks. [3] Eosinophilic bronchitis is also defined by the increased number of eosinophils, a type of white blood cell, in the sputum compared to that of healthy people. [2]
Lower respiratory infectious disease is the fifth-leading cause of death and the combined leading infectious cause of death, being responsible for 2.74 million deaths worldwide. [27] This is generally similar to estimates in the 2010 Global Burden of Disease study. [ 28 ]
A cough that is four weeks or longer in duration is considered chronic for children. [31] Most common causes for children include asthma, respiratory tract infections and GERD. An estimation of between one and 21% of children suffer from chronic cough.
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The cough may persist for several weeks afterward with the total duration of symptoms usually around three weeks. [2] [1] Some have symptoms for up to six weeks. [3] In more than 90% of cases, the cause is a viral infection. [1] These viruses may be spread through the air when people cough or by direct contact. [2]