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Pyrantel is a medication used to treat a number of parasitic worm infections. [2] This includes ascariasis , hookworm infections , enterobiasis (pinworm infection), trichostrongyliasis , and trichinellosis . [ 2 ]
Diagnosis is by seeing the worms which are about one centimetre long or the eggs under a microscope. [1] [6] Treatment is typically with two doses of the medications mebendazole, pyrantel pamoate, or albendazole two weeks apart. [4] Everyone who lives with or takes care of an infected person should be treated at the same time. [1]
Drontal (combination with pyrantel pamoate) (Bayer) for veterinary use; D-Worm for veterinary use; note that D-Worm also makes roundworm medicine containing piperidine which is not effective against tapeworms. Fish Tapes (Thomas Labs) for aquarium use; Interceptor Plus chewable tablets (combination with milbemycin) for veterinary use. Note ...
Pinworm is the most common worm infection in the U.S., and up to half of kids can become infected at some time, according to the Centers for Disease Control and Prevention. We are the only hosts ...
Pyrantel pamoate (Antiminth, Pin-Rid, Pin-X), depolarizes ganglionic block of nicotinic neuromuscular transmission, resulting in spastic paralysis of the worm. Spastic (tetanic) paralyzing agents, in particular pyrantel pamoate, may induce complete intestinal obstruction in a heavy worm load. Dosage is 11 mg/kg not to exceed 1 g as a single dose.
The most common treatments for hookworm are benzimidazoles, specifically albendazole and mebendazole. BZAs kill adult worms by binding to the nematode's β-tubulin and subsequently inhibiting microtubule polymerization within the parasite. [14] In certain circumstances, levamisole and pyrantel pamoate may be used. [12]
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