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Equine drug testing is a form of drug testing applied to performance horses in regulated competition. Most common in racehorses , drug tests are also performed on horses in endurance riding and in international competition such as the Olympics and FEI -sanctioned competition.
Nephrotoxicity is toxicity in the kidneys. It is a poisonous effect of some substances , both toxic chemicals and medications , on kidney function . [ 1 ] There are various forms, [ 2 ] and some drugs may affect kidney function in more than one way.
The LD 50 ("Lethal Dose 50%") test is used to evaluate the toxicity of a substance by determining the dose required to kill 50% of the test animal population. This test was removed from OECD international guidelines in 2002, replaced by methods such as the fixed dose procedure , which use fewer animals and cause less suffering.
Potomac Horse Fever (PHF) is a potentially-fatal febrile illness affecting horses caused by the intracellular bacterium Neorickettsia risticii. PHF is also known as Shasta River Crud and Equine Monocytic Ehrlichiosis .
The Coggins test submission form, which requires identification of the horse's physical appearance. The Coggins test (agar immunodiffusion) is a sensitive diagnostic test for equine infectious anemia developed by Dr. Leroy Coggins in the 1970s. Currently, the US does not have an eradication program due to the low rate of incidence.
Pituitary pars intermedia dysfunction (PPID), or equine Cushing's disease, is an endocrine disease affecting the pituitary gland of horses. It is most commonly seen in older animals, [1] and is classically associated with the formation of a long, wavy coat and chronic laminitis.
An early life stage (ELS) test is a chronic toxicity test using sensitive early life stages like embryos or larvae to predict the effects of toxicants on organisms. [1] ELS tests were developed to be quicker and more cost-efficient than full life-cycle tests, taking on average 1–5 months to complete compared to 6–12 months for a life-cycle test.
Equine influenza is characterized by a very high rate of transmission among horses, and has a relatively short incubation time of one to three days. [6] Clinical signs of equine influenza include fever (up to 106 °F [41 °C]), nasal discharge, have a dry, hacking cough, depression, loss of appetite and weakness. [6]