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Hemangiosarcoma is a rapidly growing, highly invasive variety of cancer that occurs almost exclusively in dogs, and only rarely in cats, horses, mice, [1] or humans (vinyl chloride toxicity). It is a sarcoma arising from the lining of blood vessels; that is, blood-filled channels and spaces are commonly observed microscopically.
Various immunosuppressive treatment regimens have been tried, but are not consistently effective. [ 13 ] [ 15 ] Treatment regimens with adrenal steroids and thyroid hormones have been proposed, but as of 2016 no controlled, peer reviewed studies had investigated the effectiveness of such treatments.
Drooling, or slobbering, is the flow of saliva outside the mouth. Drooling can be caused by excess production of saliva , inability to retain saliva within the mouth (incontinence of saliva), or problems with swallowing ( dysphagia or odynophagia ).
The Neapolitan Mastiff has a lot of excess skin plus droopy jowls which make drooling impossible to avoid. They are huge dogs, reaching weights of up to 150 pounds with a standing height of around ...
Hypersalivation can contribute to drooling if there is an inability to keep the mouth closed or difficulty in swallowing (dysphagia) the excess saliva, which can lead to excessive spitting. Hypersalivation also often precedes emesis (vomiting), where it accompanies nausea (a feeling of needing to vomit).
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Lomustine is used as an "off-label" veterinary treatment for cancers in cats and dogs. [5] Clinical trials have demonstrated the drug's success in treating progressive lymphomas, mast cell tumors, and brain cancers. [11] [12] The chemotherapy has also been used to treat sarcomas and spinal cord tumors in these animals. [5]