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LibreOffice Calc is the spreadsheet component of the LibreOffice software package. [5] [6]After forking from OpenOffice.org in 2010, LibreOffice Calc underwent a massive re-work of external reference handling to fix many defects in formula calculations involving external references, and to boost data caching performance, especially when referencing large data ranges.
sc is a cross-platform, free, TUI, spreadsheet and calculator application that runs on Unix and Unix-like operating systems. It has also been ported to Windows. It can be accessed through a terminal emulator, and has a simple interface and keyboard shortcuts resembling the key bindings of the Vim text editor. It can be used in a similar manner ...
Gnumeric has the ability to import and export data in several file formats, including CSV, Microsoft Excel (write support for the more recent .xlsx format is incomplete [5]), Microsoft Works spreadsheets (.wks), [6] HTML, LaTeX, Lotus 1-2-3, OpenDocument and Quattro Pro; its native format is the Gnumeric file format (.gnm or .gnumeric), an XML file compressed with gzip. [7]
Therefore, the total number of reads generated in a single experiment is typically normalized by converting counts to fragments, reads, or counts per million mapped reads (FPM, RPM, or CPM). The difference between RPM and FPM was historically derived during the evolution from single-end sequencing of fragments to paired-end sequencing.
Sequencing technologies vary in the length of reads produced. Reads of length 20-40 base pairs (bp) are referred to as ultra-short. [2] Typical sequencers produce read lengths in the range of 100-500 bp. [3] However, Pacific Biosciences platforms produce read lengths of approximately 1500 bp. [4] Read length is a factor which can affect the results of biological studies. [5]
Numbers works in a fashion somewhat different from traditional spreadsheets like Microsoft Excel or Lotus 1-2-3.In the traditional model, the table is the first-class citizen of the system, acting as both the primary interface for work and as the container for other types of media like charts or digital images.
Sequence coverage (or depth) is the number of unique reads that include a given nucleotide in the reconstructed sequence. [1] [2] Deep sequencing refers to the general concept of aiming for high number of unique reads of each region of a sequence. [3] Physical coverage, the cumulative length of reads or read pairs expressed as a multiple of ...
SOAP: robust with a small (1-3) number of gaps and mismatches. Speed improvement over BLAT, uses a 12 letter hash table. SOAP2: using bidirectional BWT to build the index of reference, and it is much faster than the first version. SOAP3: GPU-accelerated version that could find all 4-mismatch alignments in tens of seconds per one million reads.