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The rabies vaccine is a vaccine used to prevent rabies. [11] There are several rabies vaccines available that are both safe and effective. [ 11 ] Vaccinations must be administered prior to rabies virus exposure or within the latent period after exposure to prevent the disease. [ 12 ]
The number of recorded human deaths from rabies in the United States has dropped from 100 or more annually in the early 20th century to one or two per year because of widespread vaccination of domestic dogs and cats and the development of human vaccines and immunoglobulin treatments.
The treatment consists of a series of injections of rabies vaccine and immunoglobulin. [10] Rabies vaccine is given to both humans and animals who have been potentially exposed to rabies. [11] As of 2018, the average estimated cost of rabies post-exposure prophylaxis was US$ 108 (along with travel costs and loss of income). [12]
This approach aims to develop vaccines that are both more cost-effective and have better protective coverage, addressing the ongoing global need for rabies prevention. [46] Interestingly, the rabies virus vaccine that was created using the SAD-B19 complex, which includes the L-P protein, was utilized in the creation of a vaccine for SARS-CoV-2.
Purified duck embryo vaccine (PDEV) was the first vaccine developed for human use in treating pre- and postexposure to the rabies virus. It was developed in 1957 and was made of dried, killed rabies virus. Vaccination with PDEV involved a series of intradermal injections over several days.
In 2022, there was no human death due to rabies. [54] In November 2024, a California art teacher died from rabies, about a month after being bitten by a bat she found in her classroom. [55] In 2024, there was also a rabies human death in Minnesota (contracted from a bat), [56] and a rabies human death in Kentucky (believed to have been acquired ...
The Global Alliance for Rabies Control and its partners have reassessed the global burden of rabies, and are working on the costs of rabies and the benefits of individual large-scale rabies control programs. The global burden of rabies is now estimated to be 59,000 human lives every year, with annual economic losses of around 8.6 billion US ...
This is a timeline of the development of prophylactic human vaccines. Early vaccines may be listed by the first year of development or testing, but later entries usually show the year the vaccine finished trials and became available on the market. Although vaccines exist for the diseases listed below, only smallpox has