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Raloxifene is a selective estrogen receptor modulator (SERM) and therefore a mixed agonist–antagonist of the estrogen receptor (ER). [6] It has estrogenic effects in bone and antiestrogenic effects in the breasts and uterus. [6] Raloxifene was approved for medical use in the United States in 1997. [6] It is available as a generic medication.
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Estradiol was used as a positive control and raloxifene was used because it is in the same drug class as ospemifene. [10] Multiple doses of oral ospemifene were tested. [10] 10 mg/kg/day of Ospemifene was found to cause a greater increase in vaginal weight and vaginal epithelial height than 10 mg/kg/day of raloxifene. [10]
ZeroZeroZero is an Italian crime drama television series created by Stefano Sollima, Leonardo Fasoli and Mauricio Katz for Sky Atlantic, Canal+ and Amazon Prime Video.It is based on the non-fiction book of the same name by Roberto Saviano, [1] [2] a study of the business around the drug cocaine, covering its movement across continents.
10,000 Days is the fourth studio album by the American rock band Tool. The album was released by Tool Dissectional and Volcano Entertainment on April 28, 2006 in parts of Europe , April 29, 2006 in Australia , May 1, 2006 in the United Kingdom , and on May 2, 2006 in North America .
The antiestrogen withdrawal response is a paradoxical improvement in breast cancer caused by discontinuation of antiestrogen therapy for breast cancer. [1] [2] [3] [4 ...
Ten Thousand Days (Hungarian: Tízezer nap) is a 1967 Hungarian drama film directed by Ferenc Kósa. It was entered into the 1967 Cannes Film Festival where Kósa won the award for Best Director. [1] The film was chosen to be part of the Budapest Twelve, a list of Hungarian films considered the best in 1968. [2]
Estradiol/raloxifene (E2/RLX) is a tissue-selective estrogen complex (TSEC) which was studied for potential use in menopausal hormone therapy but was never marketed. [ 2 ] [ 1 ] [ 3 ] [ 4 ] [ 5 ] Today, E2/RLX is not generally used due to concerns of endometrial hyperplasia .
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