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Immunocompromised individuals are especially vulnerable to bacteria that are typically nonpathogenic; because of a compromised immune system, disease occurs when these bacteria gain access to the body's interior. Genes have been identified that predispose disease and infection with nonpathogenic bacteria by a small number of persons. [3]
Infectious disease – illness or disorder when pathogenic (disease-causing) microorganisms, such as bacteria, viruses, fungi, or parasites invade and multiply within the body of a host organism and release toxins, causing various clinical symptoms which can potentially lead to severe health complications or even death. Infectious diseases can ...
Most are non-infectious, although there are some non-communicable infectious diseases, such as parasitic diseases in which the parasite's life cycle does not include direct host-to-host transmission. The four main NCDs that are the leading causes of death globally are cardiovascular disease, cancer, chronic respiratory diseases, and diabetes.
Contagious disease, a subset of infectious diseases. Cryptogenic disease, a disease whose cause is currently unknown. Disseminated disease, a disease that is spread throughout the body. Environmental disease; Lifestyle disease, a disease caused largely by lifestyle choices. Localized disease, a disease affecting one body part or area. Non ...
Some diseases, such as most (but not all) forms of cancer, heart disease, and mental disorders, are non-infectious diseases. Many non-infectious diseases have a partly or completely genetic basis (see genetic disorder) and may thus be transmitted from one generation to another.
Infectious diseases are sometimes called contagious diseases when they are easily transmitted by contact with an ill person or their secretions (e.g., influenza). Thus, a contagious disease is a subset of infectious disease that is especially infective or easily transmitted. All contagious diseases are infectious, but not vice versa.
An animal model (short for animal disease model) is a living, non-human, often genetic-engineered animal used during the research and investigation of human disease, for the purpose of better understanding the disease process without the risk of harming a human. Although biological activity in an animal model does not ensure an effect in humans ...
The second experiment focused more on zoonotic pathogens being correlated with emerging infectious diseases in humans. The researchers comprised a database with separate infectious species, infectious pathogens that cause disease in patients with abnormal immune systems, and pathogens that have only been found in one case of human disease. [10]