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Because croton tiglium oil is cocarcinogenic, it has been used in tumor research. [5] Berenblum and Shubik saw croton oil as a “promoting” agent: [6] a kind of carcinogen that acted through an inflammatory response. Mice painted only with croton oil hadn’t developed tumors. Croton oil is the source of the chemical compound phorbol. [7]
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Crotonic acid has 4 carbons, is included in croton oil, and is a trans-2-mono-unsaturated fatty acid.C 3 H 5 CO 2 H, IUPAC organization name (E)-but-2-enoic acid, trans-but-2-enoic acid, numerical representation 4:1, n-1, molecular weight 86.09, melting point 72–74 °C, boiling point 180–181 °C, specific gravity 1.027.
The purging croton, Croton tiglium, is the source of croton oil from which phorbol was initially isolated. Its seeds and oil have been used for hundreds of years in traditional medicine, generally as a purgative, and the seeds were mentioned in Chinese herbal texts 2000 years ago. [15]
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Properties of vegetable oils [1] [2] The nutritional values are expressed as percent (%) by mass of total fat. Type Processing treatment [3] Saturated fatty acids Monounsaturated