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The development of the kidney proceeds through a series of successive phases, each marked by the development of a more advanced kidney: the archinephros, pronephros, mesonephros, and metanephros. [1] The pronephros is the most immature form of kidney, while the metanephros is most developed. The metanephros persists as the definitive adult kidney.
The renal tubules of the metanephros, unlike those of the pronephros and mesonephros, do not open into the Wolffian duct. Instead, the tubules rapidly elongate to form the parts of the nephron: the proximal tubules, the loops of Henle and the distal convoluted tubules. These last join and establish communications with the collecting duct system ...
In humans, the kidneys are two reddish-brown bean-shaped blood-filtering organs [1] that are a multilobar, multipapillary form of mammalian kidneys, usually without signs of external lobulation. [ 2 ] [ 3 ] They are located on the left and right in the retroperitoneal space , and in adult humans are about 12 centimetres ( 4 + 1 ⁄ 2 inches) in ...
The nephrons of the mammalian kidneys have loops of Henle, which are the most efficient way to reabsorb water and produce concentrated urine to conserve water in the body. [12] The mammalian kidneys combine both nephrons with a short and nephrons with a long loop of Henle. [77] The medulla is divided into outer and inner regions.
This illustration demonstrates the normal kidney physiology, including the Proximal Convoluted Tubule (PCT), Loop of Henle, and Distal Convoluted Tubule (DCT). It also includes illustrations showing where some types of diuretics act, and what they do. Renal physiology (Latin renes, "kidneys") is the study of the physiology of the kidney.
Scientists have grown kidneys containing mostly human cells inside pig embryos, an important step toward growing kidneys and potentially other human organs.
The unipapillary kidney with a single renal pyramid is the simplest type of kidney in mammals, from which the more structurally complex kidneys are believed to have evolved. [ 17 ] [ 6 ] [ 18 ] Differences in kidney structure are the result of adaptations during evolution to variations in body mass and habitats (in particular, aridity ) between ...
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