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Decongestants are often used in conjunction with cold medications or to combat pregnancy rhinitis in pregnant women. Common decongestants include pseudoephedrine and phenylephrine . [ 14 ] Pseudoephedrine is an alpha-adrenergic receptor agonist that enacts a vasoconstrictive effect to reduce airflow resistance in the nasal cavity and allow ...
Propylhexedrine, sold under the brand name Benzedrex among others, is a nasal decongestant of the alkylamine family and related to the arylalkylamines. [1] Its main indications are relief of congestion due to colds, allergies, and allergic rhinitis. [2]
[3] [8] The nasal spray is used for prevention and treatment of allergic rhinitis. [2] Nasal drops are used in the treatment of nasal polyps. The nasal spray can also be used in the mouth for mouth ulcers. [11] Fluticasone propionate in a topical form can be used to treat skin conditions such as eczema, psoriasis, and rashes. [17] [18]
After an FDA advisory committee said the decongestant phenylephrine, an ingredient found in many oral cold and flu medications, is ineffective, experts weigh in on alternatives.
Commonly used anti-allergic agents include antihistamines, decongestants, corticosteroids, leukotriene pathway modifiers and mast cell stabilizers. Antihistamines and decongestants are generally the first-line treatment in mild to moderate allergic reactions. Corticosteroids are generally indicated for moderate cases.
A decongestant, or nasal decongestant, is a type of pharmaceutical drug that is used to relieve nasal congestion in the upper respiratory tract. The active ingredient in most decongestants is either pseudoephedrine or phenylephrine (the latter of which has disputed effectiveness ).
A popular over-the-counter decongestant ingredient doesn’t actually work, according to advisors to the FDA. CVS plans to pull some products containing popular decongestant from shelves.
[4] [5] Use is not recommended during pregnancy. [2] Xylometazoline is in the decongestant and alpha-adrenergic agonist families of medication. [5] [6] One study classified it with selectivity ratios in alpha 2 adrenergic receptors of 151 for a2A vs a2B, 4.5 a2A vs a2C, and 33.9 a2B vs a2C. Making it a highly selective a2A agonist. [7]