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Gambierdiscus toxicus is a species of photosynthetic unicellular eukaryote belonging to the Alveolata, part of the SAR supergroup.It is a dinoflagellate which can cause the foodborne illness ciguatera, [1] and is known to produce several natural polyethers including ciguatoxin, maitotoxin, gambieric acid, and gambierol.
Opening a sodium channel causes depolarization, which could sequentially cause paralysis, heart arrhythmia, and changing the senses of heat and cold. Such poisoning from ciguatoxins is known as ciguatera. Ciguatoxins are lipophilic, able to cross the blood–brain barrier, and can cause both central and peripheral neurologic symptoms.
Disseminated protothecosis is most commonly seen in dogs. The algae enters the body through the mouth or nose and causes infection in the intestines. From there it can spread to the eye, brain, and kidneys. Symptoms can include diarrhea, weight loss, weakness, inflammation of the eye , retinal detachment, ataxia, and seizures. [11]
Afterwards, carnivorous fish, which are targeted by fishing industries, move the toxins further up the food chain. Ciguatera is the most common form of seafood poisoning caused by harmful algal blooms in the world and its incidence and range appear to spread. Best estimates indicate that more than 50,000 people are globally affected every year.
Even though ciguatera causes major gastrointestinal issues, so far P-CTX-1 hasn't been proven to have a direct effect on digestive systems. Terao et al showed that no morphological alterations were observed in the mucosa or muscle layers of the small intestine , despite the severe diarrhoea commonly observed upon P-CTX-1 administration. [ 25 ]
Ciguatera fish poisoning (CFP), also known as ciguatera, is a foodborne illness caused by eating reef fish contaminated with ciguatoxins. [ 4 ] [ 2 ] Such individual fish are said to be ciguatoxic . Symptoms may include diarrhea , vomiting, numbness, itchiness, sensitivity to hot and cold, dizziness , and weakness.
A very common foodborne illness in fish is ciguatera, which is caused by eating certain reef fishes whose flesh is contaminated with toxins. [76] The CDC states the following about Ciguatera: Ciguatera fish poisoning (or ciguatera) is an illness caused by eating fish that contain toxins produced by a marine microalgae called Gambierdiscus ...
This is a list of human deaths caused by dogs in reverse chronological order, which have been documented through news media, reports, cause-of-death statistics, scientific papers, or other sources. For additional information on causes of death and studies related to fatalities resulting from dog bites or attacks, see Fatal dog attacks .