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The Northrop Grumman B-21 Raider is an American strategic bomber in development for the United States Air Force (USAF) by Northrop Grumman. Part of the Long Range Strike Bomber (LRS-B) program, it is to be a stealth intercontinental strategic bomber that can deliver conventional and thermonuclear weapons.
Anosognosia is a condition in which a person with a disability is cognitively unaware of having it due to an underlying physical condition. Anosognosia results from physiological damage to brain structures, typically to the parietal lobe or a diffuse lesion on the fronto-temporal-parietal area in the right hemisphere, [1] [2] [3] and is thus a neuropsychiatric disorder.
Schizophreniform disorder is a type of mental illness that is characterized by psychosis and closely related to schizophrenia.Both schizophrenia and schizophreniform disorder, as defined by the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV-TR), have the same symptoms and essential features except for two differences: the level of functional impairment and the duration of symptoms.
Glutamate hypothesis of schizophrenia. The glutamate hypothesis of schizophrenia models the subset of pathologic mechanisms of schizophrenia linked to glutamatergic signaling. The hypothesis was initially based on a set of clinical, neuropathological, and, later, genetic findings pointing at a hypofunction of glutamatergic signaling via NMDA ...
The core symptoms of schizophrenia can be classified into three broad categories. These symptoms are often used to build and study animal models of schizophrenia in the field of epigenetics. [1] Positive symptoms are considered limbic system aberrations, while negative and cognitive symptoms are thought of as frontal lobe abnormalities. [4]
The dopamine hypothesis of schizophrenia or the dopamine hypothesis of psychosis is a model that attributes the positive symptoms of schizophrenia to a disturbed and hyperactive dopaminergic signal transduction. The model draws evidence from the observation that a large number of antipsychotics have dopamine- receptor antagonistic effects.
Negative symptoms, referred to as "psychomotor poverty," are linked to decreased frontal activation during tasks, resulting in slowed mental processing and planning deficits. This frontal dysfunction is specific to a sub-syndrome of schizophrenia, with three consistent syndromes: disorganization, positive, and negative.
Amotivational syndrome is a chronic psychiatric disorder characterized by signs that are linked to cognitive and emotional states such as detachment, blunted emotion and drives, executive functions like memory and attention, [1] disinterest, passivity, apathy, and a general lack of motivation.
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