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Dextroamphetamine is the dextrorotatory, or 'right-handed', enantiomer and exhibits more pronounced effects on the central nervous system than levoamphetamine. Pharmaceutical dextroamphetamine sulfate is available as both a brand name and generic drug in a variety of dosage forms.
By mouth. Dexamyl (or Drinamyl in the UK) was the brand name of a combination drug composed of amobarbital (previously called amylbarbitone) and dextroamphetamine (Dexedrine) within the same pill. It was widely abused and is no longer manufactured. [1]
[56] d-MPH has a similar side-effect profile to MPH [13] and can be administered without regard to food intake. [57] CTx-1301 is an experimental medication that is an extended-release formulation of dexmethylphenidate that has a half life more than an hour longer than extended-release dexmethylphenidate (d-MPH-ER). It is under development for ADHD.
Adderall and Mydayis[ 10 ] are trade names [ note 2 ] for a combination drug containing four salts of amphetamine. The mixture is composed of equal parts racemic amphetamine and dextroamphetamine, which produces a (3:1) ratio between dextroamphetamine and levoamphetamine, the two enantiomers of amphetamine. [ 12 ]
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Obetrol, a pharmaceutical mixture of amphetamine and methamphetamine salts, was medically indicatedand marketed for treating obesity, as illustrated in this advertisement from 1970. Amphetamine was first synthesized in 1887 in Germany by Romanian chemist, Lazăr Edeleanu, who named the drug phenylisopropylamine.
Substituted amphetamines are a class of compounds based upon the amphetamine structure; [1] it includes all derivative compounds which are formed by replacing, or substituting, one or more hydrogen atoms in the amphetamine core structure with substituents. [1][2][3][4] The compounds in this class span a variety of pharmacological subclasses ...
Eskatrol. Eskatrol was an amphetamine weight loss agent which was removed by the U.S. Food and Drug Administration (FDA) in 1981 after its manufacturer, [1] SmithKline & French (SKF), [2] failed to prove the therapeutic effectiveness (Emax) of the medication. At the time it was among the 200 most widely prescribed drugs in the United States.