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Targeted drug delivery. Targeted drug delivery, sometimes called smart drug delivery, [1] is a method of delivering medication to a patient in a manner that increases the concentration of the medication in some parts of the body relative to others. This means of delivery is largely founded on nanomedicine, which plans to employ nanoparticle ...
Drug delivery is a concept heavily integrated with dosage form and route of administration, the latter sometimes being considered part of the definition. [9] While route of administration is often used interchangeably with drug delivery, the two are separate concepts. Route of administration refers to the path a drug takes to enter the body ...
Chemotactic drug-targeting. Targeted drug delivery is one of many ways researchers seek to improve drug delivery systems' overall efficacy, safety, and delivery. Within this medical field is a special reversal form of drug delivery called chemotactic drug targeting. [1][2] By using chemical agents to help guide a drug carrier to a specific ...
Within the broad field of drug delivery, the development of stimuli-responsive drug delivery systems has created the ability to tune drug delivery systems to achieve more controlled dosing and targeted specificity based on material response to exogenous and endogenous stimuli. Endogenous stimuli consist of chemical, biological, and physical ...
pH-responsive tumor-targeted drug delivery detects the changes in the pH within the body. These polymer drug carriers carry the therapeutic drugs to allow for targeted drug delivery. The purpose of the pH- triggered drug release is to deliver the drug precisely to the area of the tumor and not activate and release the drug in healthy tissue. [ 1]
Immunoliposome therapy is a targeted drug delivery method that involves the use of liposomes (artificial lipid bilayer vesicles) coupled with monoclonal antibodies to deliver therapeutic agents to specific sites or tissues in the body. [1] The antibody modified liposomes target tissue through cell-specific antibodies with the release of drugs ...
RNA therapeutics are a new class of medications based on ribonucleic acid (RNA). Research has been working on clinical use since the 1990s, with significant success in cancer therapy in the early 2010s. [1] In 2020 and 2021, mRNA vaccines have been developed globally for use in combating the coronavirus disease (COVID-19 pandemic). [2]
Drug delivery to the brain. Drug delivery to the brain is the process of passing therapeutically active molecules across the blood–brain barrier into the brain. This is a complex process that must take into account the complex anatomy of the brain as well as the restrictions imposed by the special junctions of the blood–brain barrier.