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Normally, the pressure within the pleural cavity is slightly less than the atmospheric pressure, which is known as negative pressure. [1] When the pleural cavity is damaged or ruptured and the intrapleural pressure becomes greater than the atmospheric pressure, pneumothorax may ensue. Intrapleural pressure is different from intrathoracic pressure.
The alveolar pressure is estimated by measuring the pressure in the airways while holding one's breath. [2] The intrapleural pressure is estimated by measuring the pressure inside a balloon placed in the esophagus. [2] Measurement of transpulmonary pressure assists in spirometry in availing for calculation of static lung compliance.
Elastic recoil means the rebound of the lungs after having been stretched by inhalation, [1] or rather, the ease with which the lung rebounds. With inhalation, the intrapleural pressure (the pressure within the pleural cavity) of the lungs decreases.
Doing the same at 5500 m, where the atmospheric pressure is only 50 kPa, the intrapulmonary air pressure falls to 25 kPa. Therefore, the same change in lung volume at sea level results in a 50 kPa difference in pressure between the ambient air and the intrapulmonary air, whereas it result in a difference of only 25 kPa at 5500 m.
During inhalation, the increased volume of alveoli as a result of lung expansion decreases the intra-alveolar pressure to a value below atmospheric pressure about -1 cmH 2 O. This slight negative pressure is enough to move 500 ml of air into the lungs in the 2 seconds required for inspiration.
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Static lung compliance is the change in volume for any given applied pressure. [1] Dynamic lung compliance is the compliance of the lung at any given time during actual movement of air. Low compliance indicates a stiff lung (one with high elastic recoil ) and can be thought of as a thick balloon – this is the case often seen in fibrosis .