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  2. List of drugs by year of discovery - Wikipedia

    en.wikipedia.org/wiki/List_of_drugs_by_year_of...

    In 1907 Alfred Bertheim synthesized Arsphenamine, the first man-made antibiotic. In 1927 Erik Rotheim patented the first aerosol spray can. In 1933 Robert Pauli Scherer created a method to develop softgels. William Roberts studies about penicillin were continued by Alexander Fleming, who in 1928 concluded that penicillin had an antibiotic ...

  3. Timeline of antibiotics - Wikipedia

    en.wikipedia.org/wiki/Timeline_of_antibiotics

    1942 – gramicidin S, the first peptide antibiotic; 1942 – sulfadimidine; 1943 – sulfamerazine; 1944 – streptomycin, the first aminoglycoside [2] 1947 – sulfadiazine; 1948 – chlortetracycline, the first tetracycline; 1949 – chloramphenicol, the first amphenicol [2] 1949 – neomycin; 1950 – oxytetracycline; 1950 – penicillin G ...

  4. Discovery and development of cephalosporins - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    The first chemical compounds of the cephalosporin group were isolated from Cephalosporium acremonium, a cephalosporin-producing fungus first discovered by Giuseppe Brotzu in 1948 from a sewage outfall off the Sardinian coast. [1] From crude filtrates of the Cephalosporium acremonium culture scientists got new antibacterial activity.

  5. Timeline of biotechnology - Wikipedia

    en.wikipedia.org/wiki/Timeline_of_biotechnology

    1928 – Alexander Fleming notices that a certain mould could stop the duplication of bacteria, leading to the first antibiotic: penicillin. 1933 – Hybrid corn is commercialized. 1942 – Penicillin is mass-produced in microbes for the first time. 1950 – The first synthetic antibiotic is created.

  6. Drug discovery - Wikipedia

    en.wikipedia.org/wiki/Drug_discovery

    A 2007 report [56] found that of the 974 small molecule new chemical entities developed between 1981 and 2006, 63% were natural derived or semisynthetic derivatives of natural products. For certain therapy areas, such as antimicrobials, antineoplastics, antihypertensive and anti-inflammatory drugs, the numbers were higher. [citation needed]

  7. History of penicillin - Wikipedia

    en.wikipedia.org/wiki/History_of_penicillin

    The article was translated into Japanese, and production of penicillin was underway by 1 February 1944. By mid-May, a research team under Hamao Umezawa had tested 750 different strains of mould and found that 75 exhibited antibiotic activity. Experiments were conducted on mice to determine efficacy and toxicity.

  8. Mildred Rebstock - Wikipedia

    en.wikipedia.org/wiki/Mildred_Rebstock

    But a large part of the credit goes to pretty Dr. Mildred Rebstock, a 28-year-old research chemist." [ 3 ] Dr. Rebstock advocated for women in scientific research during an interview with the Smithsonian Institution Archives, she stated that, of all the researchers in the field only about three percent of them were women, but she would remain ...

  9. Antibiotic - Wikipedia

    en.wikipedia.org/wiki/Antibiotic

    [20] [22] These drugs were later renamed antibiotics by Selman Waksman, an American microbiologist, in 1947. [23] The term antibiotic was first used in 1942 by Selman Waksman and his collaborators in journal articles to describe any substance produced by a microorganism that is antagonistic to the growth of other microorganisms in high dilution.