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Primary polycythemia is the overproduction of red blood cells due to a primary process in the bone marrow (a so-called myeloproliferative disease). These can be familial or congenital, or acquired later in life.
In oncology, polycythemia vera (PV) is an uncommon myeloproliferative neoplasm in which the bone marrow makes too many red blood cells. [1] The majority of cases [ 2 ] are caused by mutations in the JAK2 gene, most commonly resulting in a single amino acid change in its protein product from valine to phenylalanine at position 617.
Based on 2005-2006 estimates, the Centers for Disease Control and Prevention has stated that approximately 5.5 million Americans a year are either admitted to a hospital or seen by a physician, with some form of anemia as their primary diagnosis. [4] Symptoms of anaemia include Plummer–Vinson syndrome, candidal infections.
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The first test for diagnosis myelophthisis involves looking at a small sample of blood under a microscope. Myelophthisis is suggested by the presence of red blood cells that contain nuclei or are teardrop-shaped (dacryocytes), or immature granulocyte precursor cells which indicates leukoerythroblastosis is occurring because the displaced hematopoietic cells begin to undergo extramedullary ...
polycythemia vera known as primary polycythemia has no secondary causes that can be found your oxygen levels are normal and you epo is normal or low. — Preceding unsigned comment added by 68.44.223.149 ( talk ) 07:54, 13 December 2011 (UTC) [ reply ]
The site cross-references the contents of dictionaries such as The American Heritage Dictionary of the English Language, the Collins English Dictionary; encyclopedias such as the Columbia Encyclopedia, the Computer Desktop Encyclopedia, the Hutchinson Encyclopedia (subscription), and Wikipedia; book publishers such as McGraw-Hill, Houghton Mifflin, HarperCollins, as well as the Acronym Finder ...
Ideal sources for Wikipedia's health content are defined in the guideline Wikipedia:Identifying reliable sources (medicine) and are typically review articles. Here are links to possibly useful sources of information about Polycythemia vera. PubMed provides review articles from the past five years (limit to free review articles)
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