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Among second-generation antihistamines, cetirizine is more likely than fexofenadine and loratadine to cause drowsiness. [8] Use in pregnancy appears safe, but use during breastfeeding is not recommended. [9] The medication works by blocking histamine H 1 receptors, mostly outside the brain. [6] Cetirizine can be used for paediatric patients.
The long-acting, over-the-counter medication lasts up to 24 hours per dose, according to the Food and Drug Administration (FDA). It reaches peak concentration in your body an hour after you take ...
Levocetirizine was approved for medical use in the United States in 2007, [3] and is available as a generic medication. [4] In 2022, it was the 152nd most commonly prescribed medication in the United States, with more than 3 million prescriptions. [7] [8]
The most common adverse effects noted for second-generation agents include drowsiness, fatigue, headache, nausea and dry mouth. [4] Continuous and/or cumulative use of anticholinergic medications, including first-generation antihistamines, is associated with higher risk for cognitive decline and dementia in older people. [8] [9]
Allergists explain what ingredients to look for in OTC allergy medications, and recommend their top picks for non-drowsy, pollen, runny nose, and pet dander.
Fexofenadine is used for relief from physical symptoms associated with seasonal allergic rhinitis and for treatment of hives, including chronic urticaria. [12] It does not cure, but rather prevents the aggravation of allergic rhinitis and chronic idiopathic urticaria, and reduces the severity of the symptoms associated with those conditions, providing relief from repeated sneezing, runny nose ...
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