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Generalized granuloma annulare is a chronic granulomatous dermatosis that typically affects young adults' distal extremities and manifests as annular grouped papules. [2] On the trunk and extremities, numerous flesh-colored papules arranged in an annular pattern are the hallmark of generalized granuloma annulare. These lesions are frequently ...
Granuloma annulare (GA) is a rare, [1] sometimes chronic skin condition which presents as reddish bumps on the skin arranged in a circle or ring. [2] It can initially occur at any age, though two-thirds of patients are under 30 years old, and it is seen most often in children and young adults.
Subcutaneous granuloma annulare is a skin condition of unknown cause, most commonly affecting children, with girls affected twice as commonly as boys, characterized by skin lesions most often on the lower legs.
"Pulmonary hyalinizing granuloma" is a lesion characterized by keloid-like fibrosis in the lung and is not granulomatous. Similarly, radiologists often use the term granuloma when they see a calcified nodule on X-ray or CT scan of the chest. They make this assumption since granulomas usually contain calcium, although the cells that form a ...
Histopathologically, an annular elastolytic giant-cell granuloma exhibits a granulomatous reaction accompanied by phagocytosis of the elastic fibers, elastolysis, and multinucleate giant cells devoid of or reduced in elastin fibers. Other hallmarks of the histopathology include the lack of mucin deposition and collagen necrobiosis. [7]
Perforating granuloma annulare is characterized by flesh-to-red, umbilicated papules or pustules that range in size from 1 to 5 mm. [2] These papules are frequently arranged in an annular form and frequently have an exudate, crusting, or scaling covering them. [3]
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Granuloma multiforme is a cutaneous condition most commonly seen in central Africa, and rarely elsewhere, characterized by skin lesions that are on the upper trunk and arms in sun-exposed areas. [ 2 ] : 707 It may be confused with tuberculoid leprosy , with which it has clinical similarities.