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  2. Auxotrophy - Wikipedia

    en.wikipedia.org/wiki/Auxotrophy

    In genetics, a strain is said to be auxotrophic if it carries a mutation that renders it unable to synthesize an essential compound. For example, a yeast mutant with an inactivated uracil synthesis pathway gene is a uracil auxotroph (e.g., if the yeast Orotidine 5'-phosphate decarboxylase gene is inactivated, the resultant strain is a uracil ...

  3. Candida albicans - Wikipedia

    en.wikipedia.org/wiki/Candida_albicans

    Next to the above-mentioned selection makers a few auxotrophic strains were generated to work with auxotrophic makers. The URA3 marker (URA3 blaster method) is an often-used strategy in uridine auxotrophic strains; however, studies have shown that differences in URA3 position in the genome can be involved in the pathogeny of C. albicans. [119]

  4. Kanamycin A - Wikipedia

    en.wikipedia.org/wiki/Kanamycin_A

    Mammalian cells, yeast, and other eukaryotes acquire resistance to geneticin (= G418, an aminoglycoside antibiotic similar to kanamycin) when transformed with a kanMX marker. In yeast, the kanMX marker avoids the requirement of auxotrophic markers. In addition, the kanMX marker renders E. coli resistant to kanamycin.

  5. Genetic transformation - Wikipedia

    en.wikipedia.org/wiki/Genetic_transformation

    Another method of selection is the use of certain auxotrophic markers that can compensate for an inability to metabolise certain amino acids, nucleotides, or sugars. This method requires the use of suitably mutated strains that are deficient in the synthesis or utility of a particular biomolecule, and the transformed cells are cultured in a ...

  6. Saccharomycotina - Wikipedia

    en.wikipedia.org/wiki/Saccharomycotina

    Saccharomycotina is a subdivision (subphylum) of the division (phylum) Ascomycota in the kingdom Fungi. [2] [3] It comprises most of the ascomycete yeasts.The members of Saccharomycotina reproduce by budding and they do not produce ascocarps (fruiting bodies).

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  8. List of medical roots, suffixes and prefixes - Wikipedia

    en.wikipedia.org/wiki/List_of_medical_roots...

    This is a list of roots, suffixes, and prefixes used in medical terminology, their meanings, and their etymologies. Most of them are combining forms in Neo-Latin and hence international scientific vocabulary. There are a few general rules about how they combine.

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