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  2. Grapefruit - Wikipedia

    en.wikipedia.org/wiki/Grapefruit

    Grapefruitdrug interactions are common, as the juice contains furanocoumarins that interfere with the metabolism of many drugs. This can prolong and intensify the effects of those drugs, leading to multiple side-effects such as abnormal heart rhythms, bleeding inside the stomach, low blood pressure, difficulty breathing, and dizziness.

  3. Grapefruit juice - Wikipedia

    en.wikipedia.org/wiki/Grapefruit_juice

    Grapefruit and grapefruit juice have been found to interact with numerous drugs, in many cases resulting in adverse effects. [4] This happens in two ways: one is that grapefruit can block an enzyme which metabolizes medication, [5] and if the drug is not metabolized, then the level of the drug in the blood can become too high, leading to an adverse effect. [5]

  4. Grapefruit–drug interactions - Wikipedia

    en.wikipedia.org/wiki/Grapefruitdrug_interactions

    [19] [31] For drugs recently sold on the market, drugs have information pages (monographs) that provide information on any potential interaction between a medication and grapefruit juice. [19] Because there is a growing number of medications that are known to interact with citrus, [ 1 ] patients should consult a pharmacist or physician before ...

  5. Naringenin - Wikipedia

    en.wikipedia.org/wiki/Naringenin

    Naringenin is a flavanone from the flavonoid group of polyphenols. [2] It is commonly found in citrus fruits, especially as the predominant flavonone in grapefruit. [2]The fate and biological functions of naringenin in vivo are unknown, remaining under preliminary research, as of 2024. [2]

  6. Statin - Wikipedia

    en.wikipedia.org/wiki/Statin

    The absolute prohibition of grapefruit juice consumption for users of some statins is controversial. [130] The U.S. Food and Drug Administration (FDA) notified healthcare professionals of updates to the prescribing information concerning interactions between protease inhibitors and certain statin drugs. Protease inhibitors and statins taken ...

  7. Lists of drugs - Wikipedia

    en.wikipedia.org/wiki/Lists_of_drugs

    This multi-page article lists pharmaceutical drugs alphabetically by name. Many drugs have more than one name and, therefore, the same drug may be listed more than once. Brand names and generic names are differentiated by capitalizing brand names. See also the list of the top 100 bestselling branded drugs, ranked by sales.

  8. Synephrine - Wikipedia

    en.wikipedia.org/wiki/Synephrine

    Extracts of unripe fruit from Asian cultivars of Citrus aurantium (commonly known as "bitter" orange), collected in China, were reported to contain synephrine levels of about 0.1–0.3%, or ~1–3 mg/g; [10] Analysis of dried fruit of C. aurantium grown in Italy showed a concentration of synephrine of ~1 mg/g, with peel containing over three times more than the pulp.

  9. Bergamottin - Wikipedia

    en.wikipedia.org/wiki/Bergamottin

    This prevents oxidative metabolism of certain drugs by the enzyme, resulting in an elevated concentration of drug in the bloodstream. Under normal circumstances, the grapefruit juice effect is considered to be a negative interaction, and patients are often warned not to consume grapefruit or its juice when taking medication.