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Zicam is a branded series of products marketed for cold and allergy relief whose original formulations included the element zinc.The Zicam name is derived from a portmanteau of the words "zinc" and "ICAM-1" (the receptor to which a rhinovirus binds in order to infect cells). [1]
Instances of anosmia (loss of smell) have been reported with intranasal use of some products containing zinc gluconate. In September 2003, Zicam faced lawsuits from users who claimed that the product, a nasal gel containing zinc gluconate and several inactive ingredients, negatively affected their sense of smell and sometimes taste.
The hypothesized mechanism of action by which zinc reduces the severity and/or duration of cold symptoms is the suppression of nasal inflammation and the direct inhibition of rhinoviral receptor binding and rhinoviral replication in the nasal mucosa. [1] Zinc has been known for many years to have an effect on cold viruses in the laboratory. [8]
Do not, however, use intranasal zinc. Zinc in nasal spray form can actually make you lose your sense of smell, at least temporarily, the Mayo Clinic reports. What helps with zinc absorption?
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