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The latest development in the medical treatment of acromegaly is the use of growth hormone receptor antagonists. The only available member of this family is pegvisomant (Somavert). By blocking the action of the endogenous growth hormone molecules, this compound is able to control the disease activity of acromegaly in virtually everyone with ...
Non-lifestyle risk factors include a family history of cardiomegaly, coronary artery disease (CAD), congenital heart failure, atherosclerotic disease, valvular heart disease, exposure to cardiac toxins, sleep-disordered breathing (such as sleep apnea), sustained cardiac arrhythmias, abnormal electrocardiograms, and cardiomegaly on chest X-ray.
Cardiomyopathy is a group of primary diseases of the heart muscle. [1] Early on there may be few or no symptoms. [1] As the disease worsens, shortness of breath, feeling tired, and swelling of the legs may occur, due to the onset of heart failure. [1] An irregular heart beat and fainting may occur. [1]
Heart disease is a type of cardiovascular disease that affects the heart’s structure and function. Several different heart conditions fall under the umbrella term for heart disease.
This mouse strain recapitulates many of the features of the human disease and promises to provide insights into the pathogenesis of the disease. Reducing the level of normal fibrillin 1 causes a Marfan-related disease in mice. [34] Transforming growth factor beta plays an important role in MFS. Fibrillin-1 directly binds a latent form of TGF-β ...
Acromegaly is a syndrome caused by the anterior pituitary gland producing excess growth hormone (GH). [42] A number of disorders may increase the pituitary's GH output, although most commonly it involves a tumor called pituitary adenoma , derived from a distinct type of cell ( somatotrophs ).
of or pertaining to the heart (uncommon as a prefix) Latin cor, heart commotio cordis, cornu-applied to describing processes and parts of the body as likened or similar to horns Latin cornū, horn greater cornu: coron-pertaining to the heart: Latin corōna: coronary heart disease: cortic-cortex, outer region Latin cortex, bark of a tree ...
It is believed that he died of heart disease as a complication of acromegaly. [5] A special coffin 9 feet long and 2 feet wide at the breast [12] was made for Porter and the rear doors had to be tied shut [5] as the hearse lead a parade like a procession to Cave Hill Cemetery on April 28, 1859.
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