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Sirolimus, also known as rapamycin and sold under the brand name Rapamune among others, is a macrolide compound that is used to coat coronary stents, prevent organ transplant rejection, treat a rare lung disease called lymphangioleiomyomatosis, and treat perivascular epithelioid cell tumour (PEComa).
Chemical structure of rapamycin, a pharmaceutical under evaluation for its effects on longevity. The project engages the general public to register their dogs in the studies, and therefore the project is an example of citizen science. [3] As of 2022 nearly 40,000 dogs have been registered with the project. [1]
1. Ketogenic Diet. Cancer cells rely on glucose for energy to grow. The ketogenic diet is a way to provide an alternative energy source to normal cells in the dog's body while starving the cancer ...
Comparative efficacy of two fipronil spot-on formulations against experimental tick infestations (Ixodes ricinus) in dogs. Parasitol Res. 2010 Aug;107(3):735-9. doi: 10.1007/s00436-010-1930-y ...
An equianalgesic chart can be a useful tool, but the user must take care to correct for all relevant variables such as route of administration, cross tolerance, half-life and the bioavailability of a drug. [5] For example, the narcotic levorphanol is 4–8 times stronger than morphine, but also has a much longer half-life. Simply switching the ...
The dog then causes further trauma to the skin by itching and rubbing at the area, leading to a secondary bacterial infection." Acute moist dermatitis: Symptoms.