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The low-density lipoprotein receptor (LDL-R) is a mosaic protein of 839 amino acids (after removal of 21-amino acid signal peptide) [5] that mediates the endocytosis of cholesterol-rich low-density lipoprotein (LDL).
The image above shows the interpretation of an antibody panel used in serology to detect antibodies towards the most relevant blood group antigens. Each row represents "reference" or "control" red blood cells of donors which have known antigen compositions and are ABO group O. The + symbol means that the antigen is present on the reference red ...
Apo-E interacts significantly with the low-density lipoprotein receptor (LDLR), which is essential for the normal processing of triglyceride-rich lipoproteins. [7] In peripheral tissues, Apo-E is primarily produced by the liver and macrophages , and mediates cholesterol metabolism.
Class III: LDLR does not properly bind LDL on the cell surface because of a defect in either apolipoprotein B100 (R3500Q) or in LDL-R. Class IV: LDLR bound to LDL does not properly cluster in clathrin-coated pits for receptor-mediated endocytosis (pathway step 2). Class V: LDLR is not recycled back to the cell surface (pathway step 5).
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Los Angeles Times owner Patrick Soon-Shiong, who blocked the newspaper’s endorsement of Kamala Harris and plans to overhaul its editorial board, says he will implement an artificial intelligence ...
There's no specific definition of "micro-walking," but some research has shown it's possible to get a health boost from walking as little as 10-30 seconds. And it's especially beneficial for ...
Produces antibody molecules [14] [4] Plasma cell: Lymphocyte: B cell: Plasma B cells; Effector B cells; Plasmocytus; 8-10 Active B cells that produces large amounts of antibodies [4] [15] Memory B cell: Lymphocyte: B cell: MBC; 8-10 Memorizes the characteristics of the antigens; Triggers an accelerated and robust secondary immune response [4 ...
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