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Under the brand name Prozac, fluoxetine was the first SSRI to receive approval from the FDA in the United States, in 1987. ... Like SSRIs, the side effects of SNRIs are generally mild and often ...
This is a complete list of clinically approved prescription antidepressants throughout the world, as well as clinically approved prescription drugs used to augment antidepressants or mood stabilizers, by pharmacological and/or structural classification. Chemical/generic names are listed first, with brand names in parentheses.
SNRIs are delivered orally, usually in the form of capsules or tablets. It is recommended to take SNRIs in the morning with breakfast, which does not affect drug levels, but may help with certain side effects. [48] Norepinephrine has activating effects in the body and therefore can cause insomnia in some patients if taken at bedtime. [49]
Fluvoxamine has similar side effects to other SSRIs, and it can take anywhere from six to eight weeks to feel its maximum effects. There are more serious side effects, like low sodium blood levels ...
This side effect has been particularly associated with serotonergic antidepressants like SSRIs and SNRIs, but may be less with atypical antidepressants like bupropion, agomelatine, and vortioxetine. [ 83 ] [ 85 ] [ 86 ] Higher doses of antidepressants seem to be more likely to produce emotional blunting than lower doses. [ 83 ]
In fact, since SSRIs are typically better tolerated with a lower risk of side effects, some studies have shown that fewer patients discontinue SSRI therapy than with alternative antidepressants.
For example, cocaine, which non-selectively inhibits the reuptake of serotonin, norepinephrine, and dopamine, is an SRI but not an SSRI. SRIs are used predominantly as antidepressants (e.g., SSRIs, SNRIs, and TCAs), though they are also commonly used in the treatment of other psychological conditions such as anxiety disorders and eating disorders.
Bupropion is another antidepressant used for the treatment of depression as well as seasonal affective disorder (SAD). It’s sold under the brand names: Wellbutrin. Wellbutrin SR. Wellbutrin XL ...