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  2. Rotamer - Wikipedia

    en.wikipedia.org/wiki/Rotamer

    The study of the energetics of bond rotation is referred to as conformational analysis. [6] In some cases, conformational analysis can be used to predict and explain product selectivity, mechanisms, and rates of reactions. [7] Conformational analysis also plays an important role in rational, structure-based drug design.

  3. Anti-periplanar - Wikipedia

    en.wikipedia.org/wiki/Anti-periplanar

    Anti-periplanar geometry will put a bonding orbital and an anti-bonding orbital approximately parallel to each other, or syn-periplanar. Figure 6 is another representation of 2-chloro-2,3-dimethylbutane (Figure 5), showing the C–H bonding orbital, σ C–H, and the C–Cl anti-bonding orbital, σ* C–Cl, syn-periplanar.

  4. Syn and anti addition - Wikipedia

    en.wikipedia.org/wiki/Syn_and_anti_addition

    The concepts of syn and anti addition are used to characterize the different reactions of organic chemistry by reflecting the stereochemistry of the products in a reaction. The type of addition that occurs depends on multiple different factors of a reaction, and is defined by the final orientation of the substituents on the parent molecule .

  5. Newman projection - Wikipedia

    en.wikipedia.org/wiki/Newman_projection

    The diagram takes staggered and eclipsed conformations, as well as gauche and anti interactions into account. A staggered projection appears to have the surrounding species equidistant from each other. This kind of conformation tends to experience both anti and gauche interactions. [5]

  6. Diastereomer - Wikipedia

    en.wikipedia.org/wiki/Diastereomer

    When the single bond between the two centres is free to rotate, cis/trans descriptors become invalid. Two widely accepted prefixes used to distinguish diastereomers on sp³-hybridised bonds in an open-chain molecule are syn and anti. Masamune proposed the descriptors which work even if the groups are not attached to adjacent carbon atoms.

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  9. Klyne–Prelog system - Wikipedia

    en.wikipedia.org/wiki/Klyne–Prelog_system

    Klyne notation views the placement of the substituent on the front atom as being in regions of space called anti/syn and clinal/periplanar relative to a reference group on the rear atom. A plus (+) or minus (−) sign is placed at the front to indicate the sign of the dihedral angle.