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These side effects are serious and some of them are permanent, and many remain a crucial concern for companies and healthcare professionals and substantial efforts are being encouraged to reduce the potential risks for future antipsychotics through more clinical trials and drug development.
Psoriatic erythroderma can be congenital or secondary to an environmental trigger. [12] [13] [14] Environmental triggers that have been documented include sunburn, skin trauma, psychological stress, systemic illness, alcoholism, drug exposure, chemical exposure (e.g., topical tar, computed tomography contrast material), and the sudden cessation of medication.
Crisaborole was developed by Anacor Pharmaceuticals for the topical treatment of psoriasis. [9] [6] [10] During preclinical and clinical development, crisaborole was called AN2728 and PF-06930164. [11] The drug was assumed to be potential $2bn-a-year blockbuster, when Pfizer acquired Anacor Pharmaceuticals. [12]
“Generally, the rule of thumb is that if less than 10 percent of body surface area is affected by psoriasis, topical therapy is first-line treatment,” says Dr. Nasir. Phototherapy
Psoriasis occurs when a person's immune system becomes overactive, leading to the rapid multiplication of their skin cells. This results in scaly, inflamed patches of skin, most likely on the ...
Ciclosporin, also spelled cyclosporine and cyclosporin, is a calcineurin inhibitor, used as an immunosuppressant medication.It is taken orally or intravenously for rheumatoid arthritis, psoriasis, Crohn's disease, nephrotic syndrome, eczema, and in organ transplants to prevent rejection.
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