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The Dosage Index is a mathematical figure used by breeders of Thoroughbred race horses, and sometimes by bettors handicapping horse races, to quantify a horse's ability, or inability, to negotiate the various distances at which horse races are run. It is calculated based on an analysis of the horse's pedigree.
In the laboratory, this liquid serves as a source of HCN, which is inconveniently volatile. [4] Thus, acetone cyanohydrin can be used for the preparation of other cyanohydrins, for the transformation of HCN to Michael acceptors, and for the formylation of arenes. Treatment of this cyanohydrin with lithium hydride affords anhydrous lithium cyanide:
The most important industrial application is the nickel-catalyzed synthesis of adiponitrile (NC−(CH 2) 4 −CN) synthesis from buta-1,3-diene (CH 2 =CH−CH=CH 2).Adiponitrile is a precursor to hexamethylenediamine (H 2 N−(CH 2) 6 −NH 2), which is used for the production of certain kinds of Nylon.
The race is run at either 1 + 1 ⁄ 4 miles (2,000 m) or 1 + 3 ⁄ 8 miles (2,200 m), depending on the turf course configuration at the Breeders' Cup host track. For tracks which can accommodate either distance (Belmont, Woodbine, and Santa Anita [ 1 ] ), it is run at 1 + 1 ⁄ 4 miles.
In organic chemistry, a cyanohydrin reaction is an organic reaction in which an aldehyde (−CH=O) or ketone (>C=O) reacts with a cyanide anion ...
It is used as a surrogate in place of HCN, as illustrated by its use as a precursor to lithium cyanide: [8] (CH 3) 2 C(OH)CN + LiH → (CH 3) 2 CO + LiCN + H 2. In transhydrocyanation, an equivalent of HCN is transferred from acetone cyanohydrin to another acceptor, with acetone as byproduct. The transfer is an equilibrium process, initiated by ...
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Mechanism of the Strecker-Synthesis, part 1. In the second part of the Strecker synthesis, the nitrile nitrogen of the aminonitrile is protonated, and the nitrile carbon is attacked by a water molecule. A 1,2-diamino-diol is then formed after proton exchange and a nucleophilic attack of water to the former nitrile carbon.