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CIPN afflicts between 30% and 40% of patients undergoing chemotherapy. Antineoplastic agents in chemotherapy are designed to eliminate rapidly dividing cancer cells, but they can also damage healthy structures, including the peripheral nervous system. [1] CIPN involves various symptoms such as tingling, pain, and numbness in the hands and feet. [2]
The symptoms can occur anywhere between days to months after administration of the offending medication, depending on the dose and speed of administration. [3] [4] The patient first experiences tingling and/or numbness of the palms and soles. This is followed 2–4 days later by bright redness, which is symmetrical and sharply defined. [5]
Peripheral neuropathy may first be considered when an individual reports symptoms of numbness, tingling, and pain in feet. After ruling out a lesion in the central nervous system as a cause, a diagnosis may be made on the basis of symptoms, laboratory and additional testing, clinical history, and a detailed examination.
A sore patch between the toes on Amy Jardon’s left foot was the first sign that she was suffering from acral melanoma Runner warns others after itchy spot between her toes turned out to be ...
The type of cancer Smith had, dysgerminoma, is a germ cell tumor in the ovary and the most common ovarian tumor found in women between 20 and 30, according to the National Library of Medicine.
It usually begins in the hands and feet and may progress to the arms and legs and sometimes to other parts of the body where it may affect the autonomic nervous system. It may be acute or chronic. A number of different disorders may cause polyneuropathy, including diabetes and some types of Guillain–Barré syndrome. [4] [5] [6]
What it looks like: Athlete’s foot is a rash caused by a fungal infection of the skin. People typically develop a rash between the toes, and the skin becomes white, moist, and falls apart ...
"Early delayed radiation-induced myelopathy" can manifest from six weeks to six months after treatment; the usual symptom is a Lhermitte sign ("a brief, unpleasant sensation of numbness, tingling and often electric-like discharge going from the neck to the spine and extremities, triggered by neck flexion"), usually followed by improvement two ...