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  2. Cas12a - Wikipedia

    en.wikipedia.org/wiki/Cas12a

    Like other Cas enzymes, Cas12a binds to a "guide" RNA (termed a crRNA, or CRISPR RNA) which targets it to a DNA sequence in a specific and programmable matter. In the host organism, the crRNA contains a constant region that is recognized by the Cas12a protein and a "spacer" region that is complementary to a piece of foreign nucleic acid (e.g. a ...

  3. CRISPR activation - Wikipedia

    en.wikipedia.org/wiki/CRISPR_activation

    Unlike traditional CRISPR-Cas9, which introduces double-strand breaks to edit genes, CRISPRa employs a modified, catalytically inactive Cas9 (dCas9) fused with transcriptional activators to target promoter or enhancer regions, thereby boosting gene transcription. This method allows for precise control of gene expression, making it a valuable ...

  4. These are the best Apple Black Friday deals to shop already ...

    www.aol.com/lifestyle/these-are-the-best-apple...

    The early Apple Black Friday deals have been going strong, and now that Black Friday is here, things are heating up. Right now, Amazon has drops on all favorites, with prices starting at just $24 ...

  5. iPhone 12 - Wikipedia

    en.wikipedia.org/wiki/IPhone_12

    The iPhone 12 and iPhone 12 Mini, like the iPhone 12 Pro and iPhone 12 Pro Max, are the first iPhone models from Apple to no longer include a power adapter or EarPods headphones found in prior iPhone models; however, a USB-C to Lightning cable is included; this change was retroactively applied to other iPhone models sold by Apple, such as the ...

  6. Apple debuted AI on the iPhone today. Here’s what to look out for

    www.aol.com/apple-debuted-ai-iphone-today...

    Apple sold just an estimated 37 million units in the first weekend of iPhone 16 pre-sales, down more than 12% compared to the same period last year, according to a blog post from Ming-Chi Kuo, an ...

  7. Target early Black Friday deals 2024: Start saving already on ...

    www.aol.com/lifestyle/target-early-black-friday...

    Black Friday is only a few days away, but Target Black Friday deals have already started. The bulls-eye retailer has been dropping deals left and right with savings of up to 50% on many top brands.

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