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Buspirone also seems to have lower affinities for the serotonin 5-HT 2A, 5-HT 2B, 5-HT 2C, 5-HT 6, 5-HT 7 receptors where it probably acts as an antagonist. [ 37 ] In addition to binding to serotonin receptors, buspirone is an antagonist of the dopamine D 2 receptor with weak affinity.
Special pages; Permanent link; Page information; Cite this page; Get shortened URL; Download QR code; ... Side effects of buspirone by incidence include: [1] [2] [3] [4]
A common metabolite of several azapirones including buspirone, gepirone, ipsapirone, revospirone, and tandospirone is 1-(2-pyrimidinyl)piperazine (1-PP). [47] [48] [49] 1-PP possesses 5-HT 1A partial agonist and α 2-adrenergic antagonist actions and likely contributes overall mostly to side effects. [47] [48] [50]
Vyvanse (lisdexamfetamine) – a pro-drug stimulant used to treat attention deficit hyperactivity disorder and binge eating disorder; Vyvanse is converted into Dexedrine in vivo; Viibryd – an antidepressant of the serotonin modulator and stimulators class; Vivactil (protriptyline) an antidepressant also used in the treatment of nerve pain
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Tandospirone, sold under the brand name Sediel, is an anxiolytic and antidepressant medication used in Japan and China, where it is marketed by Dainippon Sumitomo Pharma.It is a member of the azapirone class of drugs and is closely related to other azapirones like buspirone and gepirone.
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The Russell 2000 small-cap index jumped more than 5% on Wednesday for its best day in nearly two years. It closed the week up more than 8% for its best week since April 2020 and is now closing in ...