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To induce general anesthesia, propofol is the drug used almost exclusively, having largely replaced sodium thiopental. [13]It is often administered as part of an anesthesia maintenance technique called total intravenous anesthesia, using either manually programmed infusion pumps or computer-controlled infusion pumps in a process called target controlled infusion (TCI).
Propofol infusion syndrome (PRIS) is a rare syndrome which affects patients undergoing long-term treatment with high doses of the anaesthetic and sedative drug propofol. It can lead to cardiac failure , rhabdomyolysis , metabolic acidosis , and kidney failure , and is often fatal.
Close monitoring by the anesthesia provider will sometimes be provided, to help keep the patient comfortable during a medical procedure, along with other drugs to help relax the body. It can also help control breathing, blood pressure, blood flow, and heart rate and rhythm, when needed. [1] There are four levels of sedation by anesthesia.
Called target controlled infusion (TCI), it involves using a computer-controlled syringe driver (pump) to infuse propofol throughout the duration of surgery, removing the need for a volatile anaesthetic and allowing pharmacologic principles to more precisely guide the amount of the drug used by setting the desired drug concentration.
The drugs can be so dangerous, in fact, the prosecution tells jurors that doctors who use these drugs have equipment and protocols in place to revive patients if needed.
The two doctors played an integral role in Perry's untimely death, and "took advantage" of Perry's known struggle with drug addiction to make a profit, U.S. Attorney Martin Estrada said at a news ...
The public health establishment, including the National Institute on Drug Abuse and the World Health Organization, has said that medications like buprenorphine (and methadone), when coupled with counseling, give people with opioid addiction the best odds for recovery. Buprenorphine is also more difficult to misuse than heroin.
While prohibited drugs are generally viewed as being the most dangerous, the misuse of prescription drugs is linked to more deaths in several countries. [ 12 ] [ 16 ] Cocaine and heroin combined caused fewer deaths than prescriptions drugs in the United Kingdom in 2013, [ 17 ] [ 18 ] and fewer deaths than prescription opiates alone in the ...