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Clomipramine, sold under the brand name Anafranil among others, is a tricyclic antidepressant (TCA). [5] It is used in the treatment of various conditions, most notably obsessive–compulsive disorder but also many other disorders, including hyperacusis, panic disorder, major depressive disorder, trichotillomania, [6] body dysmorphic disorder [7] [8] [9] and chronic pain. [5]
Moderate dose: headache, nausea, weakness, or anxiety Large dose: loss of consciousness Perfluoroisobutene Gas: colorless Odor: none 1-4 hours Flu-like, also eye, nose, and throat irritation, and chest discomfort, or no symptoms Phosgene Gas: colorless Odor: decaying fruit, fresh-cut grass, 1-4 hours; small doses, 24-48 hours
Norclomipramine, also known as N-desmethylclomipramine and chlordesipramine, is the major active metabolite of the tricyclic antidepressant (TCA) clomipramine (Anafranil). [ 1 ] References
Children ≥6 years & adults Children ≥6 years & adults Children ≥6 years & adults Monoamine reuptake inhibitor & releasing agent: Approved: Highly efficacious, [121] therapeutic effects are usually seen within 1–3 hours of oral administration. This is a prodrug formulation of d-amp. Methamphetamine: Desoxyn [124] Not available Not available
Oral administration: In adults, 25 mg can be taken 3 to 4 times daily (up to 150 mg); in children over 5 years old, 25 mg can be taken 2 to 3 times daily. For external application, the skin or the eye conjunctiva can be treated up to several times a day by applying a thin layer of cream or ointment containing 1% chloropyramine hydrochloride.
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[1] [2] [3] Subgroup N06 is part of the anatomical group N Nervous system. [4] Codes for veterinary use (ATCvet codes) can be created by placing the letter Q in front of the human ATC code: for example, QN06. [5] ATCvet codes without corresponding human ATC codes are cited with the leading Q in the following list.
Caution is needed in prescribing imipramine (and its commercially-available metabolite, desipramine) in children and youth/adolescents (whether they suffer with, e.g., bed-wetting, recurrent panic attacks, acute trauma or, in the case of desipramine, [12] [13] ADHD), owing to possibility of certain side-effects which may be of particular ...