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As a result, dosing with a single-enantiomer form of the drug will still lead to both the enantiomers eventually being present in the patient's serum and thus would not prevent adverse effects—at best, it might reduce them if the rate of in vivo conversion can be slowed. [19] Ethambutol: Whereas the (S,S)-(+)-enantiomer is used to treat ...
Louis Pasteur - pioneering stereochemist. Chirality can be traced back to 1812, when physicist Jean-Baptiste Biot found out about a phenomenon called "optical activity." [10] Louis Pasteur, a famous student of Biot's, made a series of observations that led him to suggest that the optical activity of some substances is caused by their molecular asymmetry, which makes nonsuperimposable mirror ...
Management of tuberculosis refers to techniques and procedures utilized for treating tuberculosis (TB), or simply a treatment plan for TB.. The medical standard for active TB is a short course treatment involving a combination of isoniazid, rifampicin (also known as Rifampin), pyrazinamide, and ethambutol for the first two months.
Many times, he said, the doctors appeared indifferent to his son’s condition. “They just treat them and get them out of there,” he said. “That was hard for me…it tore me up. You just can’t explain how you see your son lying there and almost dying. There’s a couple times that I was really upset. I was mad at my son, really upset.
Trituration of the free base from cocaine hydrochloride (or "cooking") is done by dissolving the cocaine hydrochloride in water over constant heat, while simultaneously adding a base (such as baking soda) to form the free base cocaine. The free base of cocaine forms a solid "rock", pieces of which can be smoked directly (crack cocaine). [4]
9-Crown-3, also called 1,4,7-trioxonane or 1,4,7-trioxacyclononane is a crown ether with the formula (C 2 H 4 O) 3. A colorless liquid, it is obtained in low yield by the acid-catalyzed oligomerization of ethylene oxide. [1] In contrast to larger crown ethers (12-crown-4, and 18-crown-6), 9-crown-3 has elicited very little interest, except from ...
think and perform, and to empower you to new levels of personal effectiveness and fulfillment. In a three-hour process of self-discovery, you stand back, take stock and then plan the next year of your life. The exercise of answering 10 simple questions helps you to clarify your thinking and make sure your next year is the best it can be. At the end
1,4,7-Trimethyl-1,4,7-triazacyclononane is the aza-crown ether with the formula (CH 2 CH 2 NCH 3) 3. This colorless liquid is the N-methylated derivative of triazacyclononane (TACN), a face-capping tridentate ligand that is popular in coordination chemistry .