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The patch clamp technique is a laboratory technique in electrophysiology used to study ... Erwin Neher and Bert Sakmann developed the patch clamp in the late 1970s ...
This page was last edited on 26 January 2012, at 15:04 (UTC).; Text is available under the Creative Commons Attribution-ShareAlike 4.0 License; additional terms may apply.
A schematic of a patch clamp chip showing a gigaseal, whole cell recording configuration, and the ion channel and whole cell currents. Many types of systems have been developed for patch clamping cells in suspension cultures. One system uses a traditional pipette and cells in a droplet suspension culture to obtain patch clamp recordings (see ...
Erwin Neher (German pronunciation: [ˈɛʁviːn ˈneːɐ] ⓘ; / ˈ n eɪ ər /; [5] born 20 March 1944) is a German biophysicist, specializing in the field of cell physiology.For significant contribution in the field, in 1991 he was awarded, along with Bert Sakmann, the Nobel Prize in Physiology or Medicine for "their discoveries concerning the function of single ion channels in cells".
Patch-sequencing (patch-seq) is a modification of patch-clamp technique that combines electrophysiological, transcriptomic and morphological characterization of individual neurons. In this approach, the neuron's cytoplasm is collected and processed for RNAseq after electrophysiological recordings are performed on it.
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Most of this article was cut-and-pasted on Feb 22, 2005 from the voltage clamp article as part of an attempt to clean up that article. Anyone interested in the history of this article should therefore look at the voltage clamp history page prior to that date. I did not write this article.
Daughter Admits She Used to Throw Plates Away Rather Than Clean Them Up — See How Her Parents Reacted
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