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Airway clearance therapy is treatment that uses a number of airway clearance techniques to clear the respiratory airways of mucus and other secretions. [1] Several respiratory diseases cause the normal mucociliary clearance mechanism to become impaired resulting in a build-up of mucus which obstructs breathing, and also affects the cough reflex .
Chest wall oscillation is when devices are used in airway clearance therapy to clear excess mucus from lung airways (bronchi and bronchioles).It is principally used in the treatment of cystic fibrosis, but is gaining use in the treatment of other diseases, such as bronchiectasis, COPD, cerebral palsy and muscular dystrophy, in which excessive mucus can block airways due to excessive production ...
A bronchodilator or broncholytic [1] (although the latter occasionally includes secretory inhibition as well) is a substance that dilates the bronchi and bronchioles, decreasing resistance in the respiratory airway and increasing airflow to the lungs.
Mucociliary clearance has a major role in pulmonary hygiene. MCC effectiveness relies on the correct properties of the airway surface liquid produced, both of the periciliary sol layer and the overlying mucus gel layer, and of the number and quality of the cilia present in the lining of the airways. [3] An important factor is the rate of mucin ...
Mucokinetics: increase mucociliary transport (clearance) and transportability of mucus by cough [2] Mucoregulators : suppress underlying mechanisms of mucus hypersecretion [ 2 ] Alternatively, attacking the affinity between secretions and the biological surfaces is another avenue, which is used by abhesives and surfactants .
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